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phage matching

Slides each caller-supplied spacer over a bounded phage sequence in both orientations, records its minimum Hamming distance and reports matches within a caller-selected mismatch threshold. It does not account for PAMs, phage taxonomy, infection biology, escape, host range or therapeutic suitability.

POST https://bio.halowerk.com/v1/phage-matching

Eingaben

Felder des veröffentlichten Eingabeschemas
FeldTypPflichtBeschreibung
phage_sequencestringJa
spacersarrayJa
max_mismatchesintegerJa
Vollständiges Eingabeschema anzeigen
{
  "type": "object",
  "required": [
    "phage_sequence",
    "spacers",
    "max_mismatches"
  ],
  "additionalProperties": false,
  "properties": {
    "phage_sequence": {
      "type": "string",
      "minLength": 1,
      "maxLength": 10000,
      "pattern": "^[ACGT]+$"
    },
    "spacers": {
      "type": "array",
      "minItems": 1,
      "maxItems": 50,
      "items": {
        "type": "object",
        "required": [
          "id",
          "sequence"
        ],
        "additionalProperties": false,
        "properties": {
          "id": {
            "type": "string",
            "minLength": 1,
            "maxLength": 128
          },
          "sequence": {
            "type": "string",
            "minLength": 15,
            "maxLength": 60,
            "pattern": "^[ACGT]+$"
          }
        }
      }
    },
    "max_mismatches": {
      "type": "integer",
      "minimum": 0,
      "maximum": 5
    }
  }
}

Originalschema öffnen

Veröffentlichtes Eingabebeispiel

{
  "phage_sequence": "AACCGTTAGGCTAACCGTTCGATCGGATCCGAATTCGGCATGCA",
  "spacers": [
    {
      "id": "spacer-1",
      "sequence": "GGCTAACCGTTCGATC"
    },
    {
      "id": "spacer-2",
      "sequence": "ATGCCTGAATTCGGCA"
    }
  ],
  "max_mismatches": 2
}

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Quelle dieser Seite: der veröffentlichte HALOWERK-Katalog. Stand: 2026-11-01, 15:19 UTC.

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